Serologic Testing in Lyme Disease has been reviewed and is acceptable for up to 1.50 Prescribed credit(s) by the American Academy of Family Physicians.

Lyme disease can be difficult to diagnose on clinical grounds because the symptoms and signs are generally nonspecific. This module discusses how clinicians may use serologic results in their diagnostic decision-making.

After completing this module, learners should:

• Understand the role of diagnostic testing in the diagnostic process

• Understand general characteristics of diagnostic tests and their impact on test selection

• Understand the procedures for performing ELISA, Western blot and two-tier testing as well as their general sensitivity, specificity and reproducibility

• Recognize the utility and limitations of serology in Lyme disease

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